Tadalafil is an orally administered drug for treating impotence (erectile dysfunction), that initially was developed by the biotechnology company ICOS, and then developed and marketed world-wide as Cialis, by Lilly ICOS, LLC, the joint venture of ICOS Corporation and Eli Lilly and Company. Cialis tablets, in 5mg, 10mg, and 20mg doses, are yellow, film-coated, and almond-shaped. In December 2003, the Food and Drug Administration approved tadalafil (as Cialis) for sale in the U.S. as the third impotence prescription drug after sildenafil (Viagra) and vardenafil (Levitra). Cialis's 36-hour effectiveness earned it the nickname, "The Weekend Pill"; like sildenafil and vardenafil, tadalafil is recommended as a 'as needed' medication. Cialis is the only one of the three that is also offered as a once daily medication. Moreover, besides impotence, tadalafil currently is in Phase 3 clinical trials for treating pulmonary arterial hypertension.
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